产品详情
简单介绍：
Anti-Phosphoserine/threonine抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Phosphoserine/threonine抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Phosphoserine/threonine
Cat. Number:
Anti-Phosphoserine/threonine抗体KL-11994R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
A hallmark of signal transduction pathways is the reversible phosphorylation of serine and threonine residues within specific sequences, or motifs, in target proteins. Specific signaling motifs include not only sequences that are recognized
Anti-Phosphoserine/threonine抗体by protein kinases, but also those that are recognized by phosphorylation-dependent binding proteins like 14-3-3. These modular phosphoprotein interacting domains are critical elements in modulating, directing and amplifying intracellular communications. Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine surrounded by phenylalanine or tyrosine. For example, Akt, an important kinase that regulates cell survival, is activated by phosphorylation at Ser473, a site surrounded by phenylalanine and tyrosine. RSK1, p70 S6 K, and certain PKC isoforms also contain a similar consensus phosphorylation site. Phosphorylation of these sites is required for kinase activity. The Phospho-(Ser/Thr) Phe Antibody is a powerful tool for discovery of new proteins containing this important regulatory motif.
Also known as:
phospho-Ser/Phospho-Thr; pS/pT; p-S/p-T;
Anti-Phosphoserine/threonine抗体pSER/pThr; p-SER/p-Thr; p-Sp-T.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Phosphoserine/threonine.
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Immunogen: KLH conjugated synthesised
Anti-Phosphoserine/threonine抗体phosphopeptide contain Phosphoserine and Phosphothreonine.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Phosphoserine/threonine抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Phosphoserine/threonine抗体
Optimal working dilutions must be determined by the end user.
