产品详情
简单介绍：
Anti-phospho-PFKL /PFK1(Ser775)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-PFKL /PFK1(Ser775)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho-PFKL /PFK1(Ser775)
Cat. Number:
Anti-phospho-PFKL /PFK1(Ser775)抗体KL-4027R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Phosphofructokinases (PFKs) are regulatory glycolytic enzymes that catalyze the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate. Mammalian PFK is a tetramer made up of diverse combinations of three isoenzymes: muscle (PFK-1), liver (PFKL) and platelet (PFKP). PFKL (phosphofructokinase, liver),
Anti-phospho-PFKL /PFK1(Ser775)抗体also referred to as PFK-B (Phosphofructo-1-kinase isozyme B), phosphofructokinase 1 or phosphohexokinase, predominates in organs with active gluconeogenesis, such as liver and kidney. Overexpression of PFKL in transgenic mice results in a diminished glucose-induced insulin response, which suggests that PFKL may play a role in glucose-induced insulin secretion. PFKL is expressed at high levels in Down's syndrome (DS) patients, suggesting a possible role for PFKL in the pathogenesis of DS.
Also known as:
PFKL (phospho S775); PFKL (phospho Ser775); p-PFKL (Ser775); ATP-dependent 6-phosphofructokinase, liver type;
Anti-phospho-PFKL /PFK1(Ser775)抗体ATP-PFK; PFK-L; 6-phosphofructokinase type B; Phosphofructo-1-kinase isozyme B; PFK-B; Phosphohexokinase; Phosphohexokinase; PFKAL_HUMAN。
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, .
●
Immunogen: KLH conjugated
Anti-phospho-PFKL /PFK1(Ser775)抗体Synthesised phosphopeptide derived from human PFKL around the phosphorylation site of Ser775.
●
Predicted Molecular Weight: 86kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-PFKL /PFK1(Ser775)抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-phospho-PFKL /PFK1(Ser775)抗体
Optimal working dilutions must be determined by the end user.
