产品详情
简单介绍：
Anti-PHD2抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-PHD2抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-PHD2
Cat. Number:
Anti-PHD2抗体KL-3686R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
PHD2 protein catalyzes the posttranslational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. In the presence of oxygen, PHD2 converts specific prolyl residues in HIF alpha to hydroxyproline, leading to HIF alpha proteasomal degradation via the von Hippel-Lindau ubiquitylation complex. Low
Anti-PHD2抗体oxygen levels, sensed at the cellular level, cause the HIF conversion to be reduced so that HIF levels are stable. This results in increased angiogenesis as HIF1 alpha regulates the expression of many angiogenesis-related genes.
Also known as:
SM 20; Zinc finger MYND domain containing protein 6; C1ORF12; Chromosome 1 Open Reading Frame 12; ECYT 3; ECYT3;
Anti-PHD2抗体EGL 9 homolog of C. elegans 1; EGL nine (C.elegans) homolog 1; Egl nine homolog 1; Egl nine like protein 1; EGLN 1; EGLN1; HIF PH2; HIF Prolyl Hydroxylase 2; HIFP4H 2; HIFPH2; HPH 2; HPH2; Hypoxia inducible factor prolyl hydroxylase 2; ORF13; P4H2; PHD 2; PHD2; PNAS 118; PNAS 137; Prolyl Hydroxylase Domain Containing Protein 2; Rat Homolog of SM20; SM20; ZMYND6.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse,
Anti-PHD2抗体Pig, Cow, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human PHD2.
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Predicted Molecular Weight: 47kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-PHD2抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-PHD2抗体
Optimal working dilutions must be determined by the end user.
