产品详情
简单介绍：
Anti-phospho-PKC beta 1 + PKC beta 2 (Thr500)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-PKC beta 1 + PKC beta 2 (Thr500)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho-PKC beta 1 + PKC beta 2 (Thr500)
Cat. Number:
Anti-phospho-PKC beta 1 + PKC beta 2 (Thr500)抗体KL-2718R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Protein kinase C (PKC) is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Protein Kinase C beta (PKC beta) is an 80 kDa member of the conventional group (cPKCs: sensitive to diacylglycerol, Anti-phospho-PKC beta 1 + PKC beta 2 (Thr500)抗体phosphotidylserine and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival, transcriptional regulation and tumor promotion. PKC beta has been implicated in diabetes and carcinogenesis. PKC beta isoforms 1 & 2 are phosphorylated on three sites, threonine 500 in the activation loop, beta 1 threonine 642 (beta 2 641) in the turn loop and beta 1 serine 661 (beta 2 660) in the hydrophobic loop. Phosphorylation of PKC beta 1 & 2 on threonine 500 by PDK1 is a prerequisite for its autophosphoylation and catalytic competence.
Protein Kinase C beta (PKC beta) is an 80 kDa member of the conventional group (cPKCs: sensitive to diacylglycerol, Anti-phospho-PKC beta 1 + PKC beta 2 (Thr500)抗体phosphotidylserine and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival, transcriptional regulation and tumor promotion. PKC beta has been implicated in diabetes and carcinogenesis. PKC beta isoforms 1 & 2 are phosphorylated on three sites, threonine 500 in the activation loop, beta 1 threonine 642 (beta 2 641) in the turn loop and beta 1 serine 661 (beta 2 660) in the hydrophobic loop. Phosphorylation of PKC beta 1 & 2 on threonine 500 by PDK1 is a prerequisite for its autophosphoylation and catalytic competence.
Also known as:
PKC beta 1 + PKC beta 2
Anti-phospho-PKC beta 1 + PKC beta 2 (Thr500)抗体(phospho T500); PKC beta 1 + PKC beta 2 (phospho Thr500); MGC41878; PKC B; PKC beta; PKCB; PKCB1; PKCB2; PKCbeta; PRKCB 1; PRKCB 2; PRKCB; PRKCB I; PRKCB II; PRKCB1; PRKCB2; Protein kinase C beta 1; Protein kinase C beta 1; Protein kinase C beta 2; Protein kinase C beta; Protein kinase C beta type; KPCB_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, .
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Immunogen: KLH conjugated
Anti-phospho-PKC beta 1 + PKC beta 2 (Thr500)抗体Synthesised phosphopeptide derived from human PKC beta 1 around the phosphorylation site of (Thr500).
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Predicted Molecular Weight: 81kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-PKC beta 1 + PKC beta 2 (Thr500)抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-phospho-PKC beta 1 + PKC beta 2 (Thr500)抗体
Optimal working dilutions must be determined by the end user.
