产品详情
简单介绍：
Anti-Nkx2.2抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Nkx2.2抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Nkx2.2
Cat. Number:
Anti-Nkx2.2抗体KL-11302R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Members of the NK-2 family of homeodomain proteins are key regulators of growth and development in several tissues, including brain,
Anti-Nkx2.2抗体heart and pancreas. During neural development, sonic hedgehog (Shh) is known to control cell fate and mitogenesis, which is correlated with Shh dose-dependent expression of several genes, including Nkx-2.1, Nkx-2.2 and Nkx-2.9. Specifically, the Nkx-2.2 protein is responsible for directing ventral neuronal patterning in response to graded Shh signaling. In the pancreas, Nkx-2.2 is expressed in a, b and pancreatic polypeptide (PP) cells, but not in d cells. Nkx-2.2 expression is required for differentiation of pancreatic b cells, which produce insulin. Homozygous null mutations of the Nkx-2.2 gene in mice lead to severe hyperglycemia and death shortly after birth, which suggests that Nkx-2.2 may be an important therapeutic target for pancreatic diseases, including diabetes and cancer.
Also known as:
Homeobox protein NK 2 homolog B;
Anti-Nkx2.2抗体Homeobox protein NK-2 homolog B; Homeobox protein Nkx 2.2; Homeobox protein Nkx-2.2; NK 2 homolog B; NK2 homeobox 2; NK2 transcription factor like protein B; NK2 transcription factor related locus 2; NKX2 2; NKX2-2; NKX22; NKX22_HUMAN; Nkx2b; tinman.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, .
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Immunogen: KLH conjugated synthetic
Anti-Nkx2.2抗体peptide derived from human Nkx2.2.
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Predicted Molecular Weight: 30kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Nkx2.2抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Nkx2.2抗体
Optimal working dilutions must be determined by the end user.
