产品详情
  • 产品名称:Anti-NPC1抗体

  • 产品型号:尼曼匹克C1前体蛋白抗体
  • 产品厂商:KALANG
  • 产品文档:
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简单介绍:
Anti-NPC1抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-NPC1抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍:
Rabbit Anti-NPC1
Cat. Number:
Anti-NPC1抗体KL-6764R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a Anti-NPC1抗体cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009].
Also known as:
Niemann Pick C1; Niemann Pick Anti-NPC1抗体C1 protein precursor; Niemann Pick disease, type C1; Niemann-Pick C1 protein; NPC; NPC1; NPC1_HUMAN.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Chicken, Pig, Guinea Pig, .
Immunogen: KLH conjugated Anti-NPC1抗体synthetic peptide derived from mo NPC1/Niemann Pick C1.
Predicted Molecular Weight: 138kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 Anti-NPC1抗体
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

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