产品详情
简单介绍：
Anti-phospho-MEK3 (Thr222)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-MEK3 (Thr222)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho-MEK3 (Thr222)
Cat. Number:
Anti-phospho-MEK3 (Thr222)抗体KL-4123R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by
Anti-phospho-MEK3 (Thr222)抗体insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq].
Also known as:
MEK3 (phospho Thr222); MEK3
Anti-phospho-MEK3 (Thr222)抗体(phospho T222); p-MEK3 (Thr222); p-MEK3 (T222); Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; map2k3; MAPK ERK kinase 3; MAPK/ERK kinase 3; MAPKK 3; MAPKK3; MEK 3; MEK3; Mitogen activated protein kinase kinase 3; MKK3; MP2K3_HUMAN; PRKMK3.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Cow, Horse, Sheep, .
●
Immunogen: KLH conjugated Synthesised
Anti-phospho-MEK3 (Thr222)抗体phosphopeptide derived from human MEK3 around the phosphorylation site of Thr222.
●
Predicted Molecular Weight: 39kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-MEK3 (Thr222)抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-phospho-MEK3 (Thr222)抗体
Optimal working dilutions must be determined by the end user.
