产品详情
简单介绍：
Anti-Phospho-Mst1(Thr183) + Mst2(Thr180)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Phospho-Mst1(Thr183) + Mst2(Thr180)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Phospho-Mst1(Thr183) + Mst2(Thr180)
Cat. Number:
Anti-Phospho-Mst1(Thr183) + Mst2(Thr180)抗体KL-3294R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
MST1/STK4 encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B.
Anti-Phospho-Mst1(Thr183) + Mst2(Thr180)抗体The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq].
MST2/STK3, Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and Anti-Phospho-Mst1(Thr183) + Mst2(Thr180)抗体FAS ligand (MIM 134638) (Taylor et al., 1996[PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM].
MST2/STK3, Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and Anti-Phospho-Mst1(Thr183) + Mst2(Thr180)抗体FAS ligand (MIM 134638) (Taylor et al., 1996[PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM].
Also known as:
MST1/MST2 (phospho T183 + T180); MST1/MST2 (phospho T183); MST1/MST2 (phospho Thr183); Kinase responsive to stress; Krs2; Mammalian STE20 like protein kinase 1; Mammalian STE20-like protein kinase 1; Mammalian sterile 20 like 1; MST-1; Serine/threonine kinase 4; Serine/threonine protein kinase Krs 2; Serine/threonine-protein kinase 4; Serine/threonine-protein kinase Krs-2; STE20 like kinase MST1; Serine/threonine-protein kinase 4 18kDa subunit; Serine/threonine-protein kinase 4 37kDa subunit; STE20-like kinase MST1;
Anti-Phospho-Mst1(Thr183) + Mst2(Thr180)抗体STK4; STK4_HUMAN; MST1/N; MST1/C; TIIAC; YSK3.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Mst1 around the phosphorylation site of Thr183.
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Predicted Molecular Weight: 19/37/56kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Phospho-Mst1(Thr183) + Mst2(Thr180)抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Phospho-Mst1(Thr183) + Mst2(Thr180)抗体
Optimal working dilutions must be determined by the end user.
