产品详情
简单介绍：
Anti-phospho- LIM kinase 2（Ser291 + Ser293）抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho- LIM kinase 2（Ser291 + Ser293）抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho- LIM kinase 2（Ser291 + Ser293）
Cat. Number:
Anti-phospho- LIM kinase 2（Ser291 + Ser293）抗体KL-18259R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and
Anti-phospho- LIM kinase 2（Ser291 + Ser293）抗体LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Also known as:
LIM kinase 2 (phospho S291 + S293);
Anti-phospho- LIM kinase 2（Ser291 + Ser293）抗体p-LIM kinase 2 (phospho S291 + S293); LIM domain kinase 2; LIMK 2; LIMK-2; LIMK2; LIMK2_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
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Immunogen: KLH conjugated synthesised phosphopeptide derived from human LIM Kinase 1 around the phosphorylation site of
Anti-phospho- LIM kinase 2（Ser291 + Ser293）抗体（Ser291 + Ser293）.
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Predicted Molecular Weight: 72kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Anti-phospho- LIM kinase 2（Ser291 + Ser293）抗体
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
