产品详情
简单介绍：
Anti-IRX4抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-IRX4抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-IRX4
Cat. Number:
Anti-IRX4抗体KL-9464R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The Iroquois homeobox gene family of transcription factors regulate aspects of embryonic development including anterior/posterior and dorsal/ventral axis patterning in the central nervous system. The Iroquois family are clustered on two loci, IRXA and IRXB, which map to chromosomes 8 and 13 in mice. The IRXA group includes Irx1, Irx2 and Irx4; the IRXB group is comprised of Irx3, Irx5 and Irx6. Irx1 and Irx2 are both
Anti-IRX4抗体widely expressed during development in the lung epithelium and also in the ventricular septum. Irx1 and Irx2 also play a role in digit formation (E11.5–E14.5). The Irx gene family members are each expressed in a distinct pattern during mouse heart development. Specifically, Irx1 and Irx2 are expressed in the ventricular septum and Irx3 is expressed in the ventricular trabeculated myocardium. In addition, Irx4 is expressed in the linear heart tube and the AV canal, and Irx5 is expressed in the endocardium lining the ventricular and atrial myocardium. Furthermore, the IRX4 gene may modulate cardiac development and function. Although the heart of Irx4(-) mice appears to develop normally, ***** Irx4(-) mice exhibit cardiomyopathy, including cardiac hypertrophy and decreased contractility.
Also known as:
Homeodomain protein IRXA3; Iroquois
Anti-IRX4抗体Homeobox Protein 4; Iroquois-class homeodomain protein IRX-4; Iroquoisclass homeodomain protein IRX4; Irx4; IRX4_HUMAN; IRXA3.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Horse, .
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Immunogen: KLH conjugated synthetic peptide derived from human IRX4.
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Predicted Molecular Weight: 54kDa.
Anti-IRX4抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-IRX4抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-IRX4抗体
Optimal working dilutions must be determined by the end user.
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