产品详情
简单介绍:
Anti-Heparanase抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Heparanase抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍:
Rabbit Anti-Heparanase
Cat. Number:
Anti-Heparanase抗体KL-10484R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Heparanase is an endo-beta-D-glucuronidase, which degrades heparan sulfate side chains of heparan sulfate proteoglycans (HSPGs) in the extracellular matrix. Heparanase plays an important role in ECM degradation, facilitating the migration and extravasations of tumor cells and inflammatory leukocytes. Upon degradation,
Anti-Heparanase抗体heparanase releases growth factors and cytokines that stimulate cell proliferation and chemotaxis. Heparanase is a heterodimer comprised of a 50 kDa subunit harboring the active site and an 8 kDa subunit. It is produced as a latent 65 kDa precursor and proteolytically processed to its active form. Heparanase is highly expressed in myeloid leukocytes (i.e. neutrophils) in platelets and in human placenta. Human heparanase was found to be upregulated in various types of primary tumors, correlating in some cases with increased tumor invasiveness and vascularity and with poor prospective survival.
Also known as:
Heparanase 50 kDa subunit; heparanase;
Anti-Heparanase抗体heparanase1; heparanase-1; heparanase 1; Endo glucoronidase; Endo glucoronidase; Endo-glucoronidase; HPSE_HUMAN; Heparanase1; Heparanase 1; HEP; Hpa 1; HPA; Hpa1; HPR 1; HPR1; HPSE 1; HPSE; HPSE1; HSE 1; HSE1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human Heparana.
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Predicted Molecular Weight: 43kDa.
Anti-Heparanase抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Heparanase抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Heparanase抗体
Optimal working dilutions must be determined by the end user.
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