产品详情
简单介绍:
Anti-HPV18 E7抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-HPV18 E7抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍:
Rabbit Anti-HPV18 E7
Cat. Number:
Anti-HPV18 E7抗体KL-10204R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6
Anti-HPV18 E7抗体proteins form detectable complexes with p53 in vitro. Human papillomaviruses (HPV) are small DNA viruses which infect epithelia of the skin and mucosa. Over 90 types have been identified and they mostly cause a variety of benign lesions such as warts and verrucae. However, some subtypes, notably types 16 and 18, 31 and 33, have been confirmed as agents which cause cervical cancer.
Also known as:
Human Papillomavirus 18 (E7); HPV18
Anti-HPV18 E7抗体Protein E7; HPV18-E7 Protein; VE7_HPV18. Protein E7; E7; Human Papilloma Virus; Human papillomavirus type 18 E7; 8Human papillomavirus type 31 E7; Human papillomavirus type 18 E7 protein; HPV18 E7 protein.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: HPV18.
Anti-HPV18 E7抗体
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Immunogen: KLH conjugated synthetic peptide derived from HPV18 E7 Prote.
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Predicted Molecular Weight: 12kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-HPV18 E7抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-HPV18 E7抗体
Optimal working dilutions must be determined by the end user.
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