产品详情
简单介绍：
Anti-HSPG2/Heparan Sulfate Proteoglycan 2抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-HSPG2/Heparan Sulfate Proteoglycan 2抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-HSPG2/Heparan Sulfate Proteoglycan 2
Cat. Number:
Anti-HSPG2/Heparan Sulfate Proteoglycan 2抗体KL-5072R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans(heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2,
Anti-HSPG2/Heparan Sulfate Proteoglycan 2抗体FGF7 and Transthyretin, etc. and plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and Tardive dyskinesia.[provided by RefSeq, Mar 2010].
Also known as:
Heparan Sulphate Proteoglycan;
Anti-HSPG2/Heparan Sulfate Proteoglycan 2抗体Perlecan; Basement membrane specific heparan sulfate proteoglycan core protein; Endorepellin (domain V region); Heparan Sulfate Proteoglycan; Heparan sulfate proteoglycan of basement membrane; HSPG 2; HSPG; Hspg2; LG3 peptide; Perlecan; PLC antibody Schwartz Jampel syndrome 1 (chondrodystrophic myotonia); SJA antibody SJS antibody SJS1 antibody.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, .
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Immunogen: KLH conjugated synthetic peptide derived from human Heparan .
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Predicted Molecular Weight: 469kDa.
Anti-HSPG2/Heparan Sulfate Proteoglycan 2抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-HSPG2/Heparan Sulfate Proteoglycan 2抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-HSPG2/Heparan Sulfate Proteoglycan 2抗体
Optimal working dilutions must be determined by the end user.
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