产品详情
简单介绍：
Anti-HMGCR抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-HMGCR抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-HMGCR
Cat. Number:
Anti-HMGCR抗体KL-5068R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism
Anti-HMGCR抗体mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Also known as:
3H3M; HMDH_HUMAN; 3 hydroxy 3
Anti-HMGCR抗体methylglutaryl Coenzyme A reductase; 3-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; y Hmgcr; Red antibody MGC103269; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human HMGCR.
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Predicted Molecular Weight: 97kDa.
Anti-HMGCR抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-HMGCR抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-HMGCR抗体
Optimal working dilutions must be determined by the end user.
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