产品详情
简单介绍：
Anti-HER3抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-HER3抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-HER3
Cat. Number:
Anti-HER3抗体KL-2897R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation.
Anti-HER3抗体However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. Isoform 2 lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized. Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2); also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord.
Also known as:
c erbB 3; c erbB3; ERBB3; ERBB3
Anti-HER3抗体protein; erbB3 S; Glial growth factor receptor; HER 3; HER3; LCCS2; MDA BF 1; MGC88033; p180 ErbB3; p45 sErbB3; p85 sErbB3; proto-oncogene-like protein c ErbB 3; proto-oncogene-like protein c ErbB3; receptor tyrosine protein kinase ERB3; Receptor tyrosine protein kinase erbB 3; Receptor tyrosine protein kinase erbB3; Tyrosine kinase type cell surface receptor HER3; V erb b2 avian erythroblastic leukemia viral oncogene homolog 3; v erb b2 erythroblastic leukemia viral oncogene homolog 3 (avian); v erb b2 erythroblastic leukemia viral oncogene homolog 3; ERBB3_
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Guinea Pig, .
●
Immunogen: KLH conjugated synthetic peptide derived from human HER3 (15.
●
Predicted Molecular Weight: 148kDa.
Anti-HER3抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-200 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-HER3抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-HER3抗体
Optimal working dilutions must be determined by the end user.
kl971Hu01 RNA结合基元蛋白24(RBM24)多克隆抗体 Polyclonal Antibody to RNA Binding Motif Protein 24 (RBM24)
kl030Hu01 序列相似家族5成员C(FAM5C)多克隆抗体 Polyclonal Antibody to Family With Sequence Similarity 5, Member C (FAM5C)
kl142Mu01 环氧化合物水解酶4(EPHX4)多克隆抗体 Polyclonal Antibody to Epoxide Hydrolase 4 (EPHX4)
kl152Hu01 含卷曲螺旋域蛋白3(CCDC3)多克隆抗体 Polyclonal Antibody to Coiled Coil Domain Containing Protein 3 (CCDC3)
kl176Mu01 血管生成素样蛋白7(ANGPTL7)多克隆抗体 Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7)
kl493Hu01 辅酶Q10同源物B(COQ10B)多克隆抗体 Polyclonal Antibody to Coenzyme Q10 Homolog B (COQ10B)
kl574Hu01 含MOCO硫化酶羧基端域蛋白1(MOSC1)多克隆抗体 Polyclonal Antibody to MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1)
kl724Hu01 纺锤体蛋白3(SPIN3)多克隆抗体 Polyclonal Antibody to Spindlin 3 (SPIN3)
kl751Hu01 谷氨酸脱羧酶样蛋白1(GADL1)多克隆抗体 Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1)
kl758Mu01 序列相似家族135成员B(FAM135B)多克隆抗体 Polyclonal Antibody to Family With Sequence Similarity 135, Member B (FAM135B)
kl877Hu01 C1q肿瘤坏死因子相关蛋白9(C1QTNF9)多克隆抗体 Polyclonal Antibody to C1q And Tumor Necrosis Factor Related Protein 9 (C1QTNF9)
kl945Hu01 RAD54样蛋白2(RAD54L2)多克隆抗体 Polyclonal Antibody to RAD54 Like Protein 2 (RAD54L2)
kl965Hu01 跨膜蛋白2样蛋白(TMEM2L)多克隆抗体 Polyclonal Antibody to Transmembrane Protein 2 Like Protein (TMEM2L)
kl031Mu01 Misato同源物1(MSTO1)多克隆抗体 Polyclonal Antibody to Misato Homolog 1 (MSTO1)
kl085Hu01 血管紧张素1-7(Ang1-7)多克隆抗体 Polyclonal Antibody to Angiotensin 1-7 (Ang1-7)
kl092Hu01 透明质酸氨基葡糖苷酶1(HYAL1)多克隆抗体 Polyclonal Antibody to Hyaluronoglucosaminidase 1 (HYAL1)
kl134Hu01 超氧化物歧化酶(SOD)多克隆抗体 Polyclonal Antibody to Superoxide Dismutases (SOD)
kl152Hu01 丝氨酸蛋白酶33(PRSS33)多克隆抗体 Polyclonal Antibody to Protease, Serine 33 (PRSS33)
