产品详情
简单介绍：
Anti-Phospho-HER2 (Tyr1221 + Tyr1222)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Phospho-HER2 (Tyr1221 + Tyr1222)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Phospho-HER2 (Tyr1221 + Tyr1222)
Cat. Number:
Anti-Phospho-HER2 (Tyr1221 + Tyr1222)抗体KL-3212R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it
Anti-Phospho-HER2 (Tyr1221 + Tyr1222)抗体does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].
Also known as:
ErbB 2 (phospho Y1221 + Y1222);
Anti-Phospho-HER2 (Tyr1221 + Tyr1222)抗体p-ErbB 2 (phospho Y1221 + Y1222); HER2(Phospho-Tyr1221/Tyr1222); erbB-2 isoform 2; HER2 receptor; Erbb2 protein; CerbB2; c erb B2; C erbB 2; C-erbB2; CD340; Erb B2; erbb2; HER 2; HER 2/neu; HER2; Her2/neu; Herstatin; MLN 19; MLN19; NEU; NEU Proto Oncogene; Neuro Glioblastoma Derived Oncogene Homolog; NGL; p185 ErbB2; p185erbB2; Receptor Protein Tyrosine Kinase ErbB2 Precursor; Receptor tyrosine protein kinase erbB 2; TKR1; Tyrosine kinase type cell surface receptor HER2; v erb b2 erythroblastic leukemia viral oncogene homolog 2 neuro/glioblastoma derived oncogen
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Dog, Pig, Horse, Rabbit, Guinea Pig, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human.
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Predicted Molecular Weight: 138kDa.
Anti-Phospho-HER2 (Tyr1221 + Tyr1222)抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Phospho-HER2 (Tyr1221 + Tyr1222)抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Phospho-HER2 (Tyr1221 + Tyr1222)抗体
Optimal working dilutions must be determined by the end user.
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