产品详情
简单介绍：
Anti-FOXO1 + FOXO3 + FOXO4抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-FOXO1 + FOXO3 + FOXO4抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-FOXO1 + FOXO3 + FOXO4
Cat. Number:
Anti-FOXO1 + FOXO3 + FOXO4抗体KL-7068R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
FOXO1 + FOX3 + FOX4 belong to the forkhead family of transcription factors. FOXO1 (FKHR or ForkHead in Rhabdomyosarcoma) is a 70 kDa protein. Recent studies have shown that this protein can act as either a coactivator or a
Anti-FOXO1 + FOXO3 + FOXO4抗体corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C terminus of the FOXO1A protein. The specific function of the gene has not yet been determined. FOX3 probably functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of the FOXO3 gene with the MLL gene is associated with secondary acute leukemia. FOX4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.
Also known as:
AFX1; FOXO1+FOXO3+FOXO4; FKH1;
Anti-FOXO1 + FOXO3 + FOXO4抗体FKHRL1; FKHRL1P2; Forkhead box O1; Forkhead box O3; Forkhead box O4; FOXO1; FOXO2; FOXO3; FOXO4; MLLT7; FOXO1_HUMAN; FOXO3_HUMAN; FOXO4_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human FOXO1/FO.
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Predicted Molecular Weight:
Anti-FOXO1 + FOXO3 + FOXO4抗体70kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-FOXO1 + FOXO3 + FOXO4抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-FOXO1 + FOXO3 + FOXO4抗体
Optimal working dilutions must be determined by the end user.
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