产品详情
  • 产品名称:Anti-Epsin 3抗体

  • 产品型号:EPN3蛋白抗体
  • 产品厂商:KALANG
  • 产品文档:
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简单介绍:
Anti-Epsin 3抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Epsin 3抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍:
Rabbit Anti-Epsin 3
Cat. Number:
Anti-Epsin 3抗体KL-14613R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Epsin 3 is a 632 amino acid member of the epsin protein family. Epsin 3 localizes mainly to the perinuclear region of the nucleus and in clathrin-coated vesicles close to the cell periphery. Epsin 3 is expressed in migrating keratinocytes from wounded skin, but not in normal skin or differentiating keratinocytes. Epsin 3 contains one Anti-Epsin 3抗体ENTH (epsin N-terminal homology) domain and two UIM (ubiquitin-interacting motif) repeats and is expressed as two isoforms produced by alternative splicing. The gene that encodes epsin 3 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Also known as:
EPN3 EPN 3; EPN3_HUMAN; Anti-Epsin 3抗体EPS 15 interacting protein 3; Epsin-3; Epsin3; FLJ20778; MGC129899.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, .
Immunogen: KLH conjugated synthetic peptide derived from human Epsin 3.
Predicted Molecular Weight: Anti-Epsin 3抗体68kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Epsin 3抗体
Optimal working dilutions must be determined by the end user.
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