产品详情
简单介绍：
Anti-EID2抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-EID2抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-EID2
Cat. Number:
Anti-EID2抗体KL-13761R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
As a regulator of transcription via chromatin remodeling, p300 is a histone acetyltransferase that binds to adenovirus E1A protein
Anti-EID2抗体and may play a role in its transforming capacity. EID-2 (EP300-interacting inhibitor of differentiation 2), also known as CREBBP/EP300 inhibitor 2, is a 236 amino acid nuclear protein that cooperates with EID-2B to bind to the C-terminus of p300 to inhibit its activity. It also represses MYOD-dependent transcription and muscle differentiation. By interacting with SMAD2, SMAD3 and SMAD4, EID-2 selectively blocks the formation of TGFB-induced SMAD3-SMAD4 complex, thereby repressing TGFB/SMAD3-dependent signaling. Though it is abundantly expressed in placenta, EID-2 is highly expressed in skeletal muscle, heart, liver, brain and kidney. There are two isoforms of EID-2 that are produced as a result of alternative splicing events.
Also known as:
CREBBP/EP300 inhibitor 2;
Anti-EID2抗体CREBBP/EP300 inhibitory protein 2; CRI2; E1A like inhibitor of differentiation 2; EID-1-like inhibitor of differentiation 2; EID-2; EID2; EID2_HUMAN; EP300-interacting inhibitor of differentiation 2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse,
Anti-EID2抗体Rat, Pig, Cow, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human EID2.
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Predicted Molecular Weight: 25kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Anti-EID2抗体
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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