产品详情
简单介绍：
Anti-Ep300抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Ep300抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Ep300
Cat. Number:
Anti-Ep300抗体KL-6954R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE). Many transcription factors bind to this element, including the protein CREB which is activated as
Anti-Ep300抗体a result of phosphorylation by protein kinase A. It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein). These findings suggest that CBP has many of the properties expected of a CREB co-activator. Another high molecular weight transcriptional adapter protein, designated p300, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein. p300 molecules lacking an intact E1A binding site bypass E1A repression even in the presence of high concentrations of E1A. Sequence analysis of CBP and p300 has revealed substantial homology, arguing that these proteins are members of a conserved family of co-activators.
Also known as:
CREBBP/EP300 inhibitory protein 1;
Anti-Ep300抗体Cyclic AMP responsive enhancer binding protein; E1A associated protein p300; E1A binding protein p300; E1A-associated protein p300; EC 2.3.1.48; EP300; EP300: E1A binding protein p300; EP300_HUMAN; istone acetyltransferase p300; 300 HAT; RB and P300 binding protein EID 1; Retinoblastoma protein associated protein; RSTS2.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat,
Anti-Ep300抗体Dog, Pig, Cow, Horse, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human KAT3B/p3.
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Predicted Molecular Weight: 264kDa.
Storage:
Shipped at 4℃, Store at -20℃
Anti-Ep300抗体(Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Ep300抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Ep300抗体
Optimal working dilutions must be determined by the end user.
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