产品详情
简单介绍：
Anti-Phospho-Estrogen Receptor alpha (Tyr537)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Phospho-Estrogen Receptor alpha (Tyr537)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Phospho-Estrogen Receptor alpha (Tyr537)
Cat. Number:
Anti-Phospho-Estrogen Receptor alpha (Tyr537)抗体KL-1643R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Estrogen and progesterone
Anti-Phospho-Estrogen Receptor alpha (Tyr537)抗体receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER Alpha and ER Beta. ER Alpha and ER Beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.
Also known as:
Estrogen Receptor alpha (phospho Y537);
Anti-Phospho-Estrogen Receptor alpha (Tyr537)抗体p-Estrogen Receptor alpha (phospho Y537); ER alpha (Phospho-Tyr537); ER alpha (Phospho-Y537); Phospho-ER alpha (Y537); Phospho-ER alpha (Tyr537); p-ER alpha (Tyr537); p-ER alpha (Y537); Phospho-Estrogen Receptor alpha (Y537); Phospho-Estrogen Receptor alpha (Tyr537); Estradiol receptor; Estrogen receptor alpha; Estradiol Receptor-alpha; Estrogen Receptor 1; Atherosclerosis, susceptibility to, included; DKFZp686N23123; ER Alpha; ER; ER-alpha; ERalpha; ER[a]; Era; ESR; ESR1; ESR1_HUMAN; ESR2; ESRA; Estr; Estrogen receptor 1 (alpha); Estrogen resistance, in
Specificity:
●
Rabbit Polyclonal IgG, affinity purified
Anti-Phospho-Estrogen Receptor alpha (Tyr537)抗体by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Cow, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human.
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Predicted Molecular Weight: 66kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Phospho-Estrogen Receptor alpha (Tyr537)抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Phospho-Estrogen Receptor alpha (Tyr537)抗体
Optimal working dilutions must be determined by the end user.
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