产品详情
简单介绍：
Anti-Doppel抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Doppel抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Doppel
Cat. Number:
Anti-Doppel抗体KL-11732R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Prion diseases or transmissible spongiform encephalopathies (TSEs) are manifested as genetic, infectious or sporadic, lethal neurodegenerative disorders involving alterations of the prion protein (PrP). Infectious PrPSc is highly expressed in the brain of animals affected by TSEs, including scrapie
Anti-Doppel抗体in sheep, BSE in cattle, and Cruetzfeldt-Jacob disease in humans. The PRND gene locus, located on human chromosome 20p, encodes for the doppel protein (Dpl), which exhibits approximately 25% sequence homology with PrP. Dpl is characterized by an alpha-helical conformation, intramolecular disulfide bonds, and two N-linked oligosaccharides, and it is presented on the cell surface by a glycosylphosphatidylinositol anchor. Dpl is highly expressed in ***** testis and heart and is detectable in the brain of neonatal mice. Dpl does not appear to contribute to prion disease progression, but ectopic expression of Dpl is implicated in neuronal degeneration of ataxic PRP-deficient mice. Dpl is also thought to play a role in angiogenesis, specifically maturation of the blood-brain barrier.
Also known as:
DPL; Dublet; MGC41841;
Anti-Doppel抗体Prion gene complex downstream; Prion like protein doppel; Prion protein 2 (dublet); Prion protein 2; Prion-like protein doppel; PRND; PRND_HUMAN; PrPLP.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, Cow, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Doppe1 (.
●
Predicted Molecular Weight: 14kDa.
Storage:
Shipped at 4℃, Store at -20℃
Anti-Doppel抗体(Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions Anti-Doppel抗体must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions Anti-Doppel抗体must be determined by the end user.
kl848Ra01 糖原磷酸化酶M(PYGM)多克隆抗体 Polyclonal Antibody to Glycogen Phosphorylase, Muscle (PYGM)
kl849Hu01 糖原磷酸化酶L(PYGL)多克隆抗体 Polyclonal Antibody to Glycogen Phosphorylase, Liver (PYGL)
kl849Mu01 糖原磷酸化酶L(PYGL)多克隆抗体 Polyclonal Antibody to Glycogen Phosphorylase, Liver (PYGL)
kl849Ra01 糖原磷酸化酶L(PYGL)多克隆抗体 Polyclonal Antibody to Glycogen Phosphorylase, Liver (PYGL)
kl850Hu01 肿瘤坏死因子配体超家族成员4(TNFSF4)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4)
kl852Hu01 蛋白酶激活受体2(kl2)多克隆抗体 Polyclonal Antibody to Protease Activated Receptor 2 (kl2)
kl852Mu01 蛋白酶激活受体2(kl2)多克隆抗体 Polyclonal Antibody to Protease Activated Receptor 2 (kl2)
kl852Ra01 蛋白酶激活受体2(kl2)多克隆抗体 Polyclonal Antibody to Protease Activated Receptor 2 (kl2)
kl853Hu01 胱天蛋白酶8(CASP8)多克隆抗体 Polyclonal Antibody to Caskle 8 (CASP8)
kl853Mu01 胱天蛋白酶8(CASP8)多克隆抗体 Polyclonal Antibody to Caskle 8 (CASP8)
kl853Ra01 胱天蛋白酶8(CASP8)多克隆抗体 Polyclonal Antibody to Caskle 8 (CASP8)
kl855Ga01 核因子κB受体激活因子配基(RANκL)多克隆抗体 Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)
kl855Hu01 核因子κB受体激活因子配基(RANκL)多克隆抗体 Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)
kl855Mu01 核因子κB受体激活因子配基(RANκL)多克隆抗体 Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)
kl855Ra01 核因子κB受体激活因子配基(RANκL)多克隆抗体 Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)
