产品详情
简单介绍：
Anti-CSN7b抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-CSN7b抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-CSN7b
Cat. Number:
Anti-CSN7b抗体KL-11540R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The COP9 signalosome (CSN) complex is involved in several different developmental and cellular processes. The complex is made up of several widely expressed proteins: CSN1 (COPS1), CSN2 (COPS2), CSN3 (COPS3), CSN4 (COPS4), CSN5 (COPS5), CSN6 (COP6), CSN7a (COPS7, COPS7a) or CSN7b (COP7b) and CSN8 (COP8). The CSN complex acts as a regulator for the ubiquitin conjugation pathway
Anti-CSN7b抗体by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-complexes. It is also involved in the phosphorylation of p53, c-Jun, I˚Bå and IRF-8, as well as CSN-dependent phosphorylation of p53, and c-Jun protects and promotes degradation by the Ubl system. CSN7 is phosphorylated by CK2 and is composed of two subunits; a and b. CSN7a contains a PCI (Proteasome CSN9 initiation factor 3) region, as well as a coiled-coil region and is predicted to interact with CSN2, CSN3, CSN4, CSN5, CSN6, CSN8, and GPS1. CSN7b contains only a PCI region and is predicted to interact with INT6.
Also known as:
COP9 Complex Homolog
Anti-CSN7b抗体Subunit 7b; COP9 Constitutive Photomorphogenic Homolog Subunit 7b; COP9 Signalasome Subunit 7b; COP9 signalosome complex subunit 7b; COPS7B; CSN7B_HUMAN; JAB1 Containing Signalosome Subunit 7b; JAB1-containing signalosome subunit 7b; SGN7b; Signalosome subunit 7b.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human CSN7b (201-264aa).
●
Predicted Molecular Weight: 29kDa.
Storage:
Shipped at 4℃, Store
Anti-CSN7b抗体at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-CSN7b抗体dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-CSN7b抗体dilutions must be determined by the end user.
kl085Rb51 Ⅰ类主要组织相容性复合体A(MHCA)多克隆抗体 Polyclonal Antibody to Major Histocomklibility Complex Class I A (MHCA)
kl096Mu01 整合素α10(ITGα10)多克隆抗体 Polyclonal Antibody to Integrin Alpha 10 (ITGa10)
kl108Ra01 生长分化因子1(GDF1)多克隆抗体 Polyclonal Antibody to Growth Differentiation Factor 1 (GDF1)
kl111Mu01 生长分化因子6(GDF6)多克隆抗体 Polyclonal Antibody to Growth Differentiation Factor 6 (GDF6)
kl241Ra01 端粒酶逆转录酶(TERT)多克隆抗体 Polyclonal Antibody to Telomerase Reverse Transcriptase (TERT)
kl500Mu01 胃动蛋白1(GKN1)多克隆抗体 Polyclonal Antibody to Gastrokine 1 (GKN1)
kl500Po01 胃动蛋白1(GKN1)多克隆抗体 Polyclonal Antibody to Gastrokine 1 (GKN1)
kl501Mu01 乙二醛酶Ⅰ(GLO1)多克隆抗体 Polyclonal Antibody to Glyoxalase I (GLO1)
kl520Ra01 透明质酸合酶1(HAS1)多克隆抗体 Polyclonal Antibody to Hyaluronan Synthase 1 (HAS1)
kl102Hu01 低密度脂蛋白受体相关蛋白5(LRP5)多克隆抗体 Polyclonal Antibody to Low Density Lipoprotein Receptor Related Protein 5 (LRP5)
kl152Ra01 衰老关键蛋白2(FBLN2)多克隆抗体 Polyclonal Antibody to Fibulin 2 (FBLN2)
kl153Ra01 衰老关键蛋白5(FBLN5)多克隆抗体 Polyclonal Antibody to Fibulin 5 (FBLN5)
kl231Mu01 骨骼肌慢肌肌钙蛋白T(TNNT1)多克隆抗体 Polyclonal Antibody to Troponin T Type 1, Slow Skeletal (TNNT1)
kl231Ra01 骨骼肌慢肌肌钙蛋白T(TNNT1)多克隆抗体 Polyclonal Antibody to Troponin T Type 1, Slow Skeletal (TNNT1)
kl416Hu01 肌球蛋白重链4(MYH4)多克隆抗体 Polyclonal Antibody to Myosin Heavy Chain 4, Skeletal Muscle (MYH4)
kl420Ra01 肌球蛋白重链11(MYH11)多克隆抗体 Polyclonal Antibody to Myosin Heavy Chain 11, Smooth Muscle (MYH11)
