产品详情
简单介绍：
Anti-Nucleolin/C23抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Nucleolin/C23抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Nucleolin/C23
Cat. Number:
Anti-Nucleolin/C23抗体KL-8536R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Nucleolin is the major nucleolar protein of growing eukaryotic cells. C23 (nucleolin, NCL) is a eukaryotic nucleolar phosphoprotein that influences synthesis and maturation of ribosomes. C23 localizes to dense fibrillar
Anti-Nucleolin/C23抗体regions of the nucleolus. It contains four RNA binding domains that interact with pre-rRNA during synthesis. C23 can influence RNA processing, ribosomal gene transcription and nucleolar targeting of ribosomal components. It is known to associate with a variety of proteins, including the nucleolar protein B23. Phosphorylation by Cdc2 and casein kinase II causes translocation of C23 from the nucleolus to the cytoplasm. Mitotic phosphorylated forms of Bcl-2 are present in nuclear structures in prophase Hela cells together with C23 and Ki-67. Retinoic acid-induced apoptosis leads to C23 down-regulation and Bcl-2 mRNA instability. C23 binds the human telomerase reverse transcriptase subunit (TERT) through interactions with its RNA binding domain 4 and carboxyl-terminal RGG domain, and this interaction is critical for the nucleolar localization of human TERT.
Also known as:
C23; NCL; Nucl; NUCL_HUMAN;
Anti-Nucleolin/C23抗体Nucleolin; Protein C23.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Nucleolin.
●
Predicted Molecular Weight: 76kDa.
Storage:
Shipped at 4℃, Store
Anti-Nucleolin/C23抗体at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-F=1:100-500 Flow-Cyt=1:20-200 IF=1:50-200
Not yet tested in other applications.
Optimal working Anti-Nucleolin/C23抗体dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-Nucleolin/C23抗体dilutions must be determined by the end user.
kl675Po01 凝血因子Ⅴ(F5)多克隆抗体 Polyclonal Antibody to Coagulation Factor V (F5)
kl030Mu01 蛋白酪氨酸磷酸酶受体C(PTPRC)多克隆抗体 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (PTPRC)
kl045Rb51 蛋白激酶Cβ1(PKCβ1)多克隆抗体 Polyclonal Antibody to Protein Kinase C Beta 1 (PKCb1)
kl167Mu01 CD4分子(CD4)多克隆抗体 Polyclonal Antibody to Cluster Of Differentiation 4 (CD4)
kl167Si01 CD4分子(CD4)多克隆抗体 Polyclonal Antibody to Cluster Of Differentiation 4 (CD4)
kl171Mu01 转铁蛋白受体(TFR)多克隆抗体 Polyclonal Antibody to Transferrin Receptor (TFR)
kl171Po01 转铁蛋白受体(TFR)多克隆抗体 Polyclonal Antibody to Transferrin Receptor (TFR)
kl245Mu01 唾液酸结合Ig样凝集素12(SIGLEC12)多克隆抗体 Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12)
kl336Mu01 保护素(CD59)多克隆抗体 Polyclonal Antibody to Protectin (CD59)
kl336Ra01 保护素(CD59)多克隆抗体 Polyclonal Antibody to Protectin (CD59)
kl336Rb51 保护素(CD59)多克隆抗体 Polyclonal Antibody to Protectin (CD59)
kl477Mu01 基质Gla蛋白(MGP)多克隆抗体 Polyclonal Antibody to Matrix Gla Protein (MGP)
kl793Ra01 S100钙结合蛋白A9(S100A9)多克隆抗体 Polyclonal Antibody to S100 Calcium Binding Protein A9 (S100A9)
kl908Hu02 聚集蛋白聚糖(AGC)多克隆抗体 Polyclonal Antibody to Aggrecan (AGC)
kl956Ra01 谷胱甘肽S转移酶α5(GSTα5)多克隆抗体 Polyclonal Antibody to Glutathione S Transferase Alpha 5 (GSTa5)
